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Structure of 191602-54-7
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3-Bromo-4-(trifluoromethoxy)aniline features a trifluoromethoxy group that enhances electron-withdrawing character and metabolic stability. The bromo substituent enables facile cross-coupling reactions, while the aniline scaffold provides a handle for conjugation. This compound serves as a key intermediate in pharmaceutical synthesis and functional material design under standard conditions.
3-Bromo-4-(trifluoromethoxy)aniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its bromo substituent. The trifluoromethoxy group imparts enhanced metabolic stability and lipophilicity, while the aniline functionality supports further derivatization via acylation, diazotization, or electrophilic substitution. Its bench-stable, crystalline form facilitates handling and purification in multi-step syntheses.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: