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Structure of 19194-62-8
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1H-indole-3-carbonyl cyanide features a reactive nitrile group appended to an indole scaffold, enabling direct incorporation into heterocyclic frameworks. This electrophilic moiety facilitates efficient C–C bond formation under mild conditions, particularly in transition-metal-catalyzed coupling reactions. The molecule exhibits enhanced stability compared to analogous acyl cyanides and is compatible with common organic solvents, simplifying handling in synthetic workflows.
1H-indole-3-carbonyl cyanide serves as a versatile building block for indole-based heterocyclic synthesis, enabling direct introduction of the indole-3-carbonyl moiety into target molecules. Its nitrile functionality facilitates downstream transformations such as hydrolysis to carboxylic acids or reductive conversion to aldehydes, while maintaining compatibility with common functional groups. The compound exhibits bench stability and is well-suited for use in medicinal chemistry campaigns requiring rapid scaffold diversification.
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GHS Pictogram :
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GHS No : GHS06,GHS09
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅱ
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Hazard Statements : H300-H311+H331-H315-H319-H400
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Precautionary Statements : P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P361-P391-P405-P501
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Lot numbers can be found on the outside label of a product: