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Structure of 192447-58-8
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2,6-Dibromo-N,N-dimethylpyridin-4-amine features two bromine substituents at the 2 and 6 positions of a pyridine ring, flanking a dimethylamino group at the 4-position. This electron-rich scaffold enables efficient coupling in cross-coupling reactions, particularly in Pd-catalyzed transformations. The steric shielding from the N,N-dimethyl groups enhances stability under reaction conditions. The molecule exhibits excellent solubility in common organic solvents, facilitating handling in synthetic workflows.
2,6-Dibromo-N,N-dimethylpyridin-4-amine serves as a versatile building block for the synthesis of functionalized pyridine derivatives. The dibromo substitution pattern enables sequential cross-coupling reactions, while the N,N-dimethylamino group enhances electron density at C4, facilitating palladium-catalyzed coupling and enabling access to complex heterocyclic scaffolds used in medicinal chemistry and materials science. The compound exhibits good bench stability and is readily purified by column chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: