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Structure of 193140-71-5
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Ethyl 2-amino-3,3,3-trifluoropropanoate hydrochloride features a trifluoromethyl group that enhances metabolic stability and lipophilicity. The amine functionality enables direct derivatization, while the ethyl ester serves as a handle for subsequent transformations. This bench-stable salt form improves solubility and handling in synthetic workflows.
Ethyl 2-amino-3,3,3-trifluoropropanoate hydrochloride serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated bioactive scaffolds. The trifluoromethyl group imparts metabolic stability and enhanced lipophilicity, while the amino and ester functionalities offer orthogonal reactivity for peptide coupling, amidation, or heterocycle formation. Bench-stable and readily purified by standard techniques, it functions effectively in multi-step syntheses requiring robust functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P338-P362-P501
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Lot numbers can be found on the outside label of a product: