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Structure of 19335-11-6
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5-Amino-1H-indazole is a nitrogen-rich heterocyclic scaffold featuring a primary amine at the 5-position, enabling straightforward derivatization. This electron-donating amino group enhances solubility and reactivity in synthetic transformations. The fused bicyclic core imparts metabolic stability and planarity, making it valuable for medicinal chemistry and materials science applications.
5-Amino-1H-indazole serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive heterocycles via standard coupling reactions. Its amino group facilitates derivatization through acylation, alkylation, and transition-metal-catalyzed transformations, while the indazole core exhibits favorable stability and solubility for bench-scale synthesis. Functions effectively in the construction of kinase inhibitors and other pharmaceutical scaffolds.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: