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Structure of 193354-13-1
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5-Iodoindolin-2-one delivers a reactive iodine handle at the 5-position of the indolin-2-one scaffold, enabling efficient late-stage functionalization in medicinal chemistry. This bench-stable, moisture-tolerant compound integrates readily into cross-coupling workflows, facilitating the construction of diverse heterocyclic architectures with high functional group compatibility.
5-Iodoindolin-2-one serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biologically relevant indole scaffolds. The iodine substituent provides high reactivity in Suzuki, Stille, and Negishi couplings, while the indolin-2-one core offers inherent stability and compatibility with diverse functional groups. Its bench-stable nature and straightforward purification facilitate integration into multi-step syntheses of targeted compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: