tert-Butyl 1-ethynyl-3-azabicyclo[3.1.0]hexane-3-carboxylate

Name: tert-Butyl 1-ethynyl-3-azabicyclo[3.1.0]hexane-3-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1936077-76-7
Cat. No. CS-0048476
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 1-ethynyl-3-azabicyclo[3.1.0]hexane-3-carboxylate|CS-0048476

Structure of 1936077-76-7

Size

Price

Quantity

* Please select Quantity before adding items.

Description

tert-Butyl 1-ethynyl-3-azabicyclo[3.1.0]hexane-3-carboxylate is a sterically hindered, bench-stable alkyne-containing building block featuring a strained azabicyclic core. This structure enables efficient copper-catalyzed cycloadditions and facilitates the incorporation of functionalized alkynes into complex molecular architectures.

Application

tert-Butyl 1-ethynyl-3-azabicyclo[3.1.0]hexane-3-carboxylate serves as a versatile building block for the synthesis of nitrogen-containing heterocycles, particularly in the construction of constrained bicyclic scaffolds. Its terminal alkyne functionality enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), facilitating rapid access to triazole-linked architectures. The tert-butyl ester group offers stability and ease of purification, while the bicyclic core provides defined stereochemistry and rigidity beneficial for medicinal chemistry applications.

General Information

CAS No. 1936077-76-7
Cat. No. CS-0048476
Purity ≥98%
MDL No. None
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₁₇NO₂
Molecular Weight 207.27
Synonym(s) 3-Azabicyclo[3.1.0]hexane-3-carboxylic acid, 1-ethynyl-, 1,1-dimethylethyl ester
SMILES CC(C)(C)OC(=O)N1CC2CC2(C1)C#C

Computational Chemistry Data

TPSA 29.54
LogP 1.8766
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Fatty ring compounds Cyclopropane compounds

Building Blocks Skeleton Bridge Rings compounds Other bridge ring compounds

Key Words

1936077-76-7 sigma1936077-76-7 manufacturer1936077-76-7 price1936077-76-7 structure1936077-76-7 SDSbuy 1936077-76-71936077-76-7 supplier1936077-76-7 uses1936077-76-7 molecular weightprice of 1936077-76-71936077-76-7 chemical name formula of 1936077-76-7

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl 1-ethynyl-3-azabicyclo[3.1.0]hexane-3-carboxylate

CAS No. 1936077-76-7

Recommended Products