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Structure of 1942072-67-4
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This boronic acid features a trifluoromethoxy group flanked by chlorine and phenyl functionalities, delivering enhanced stability and reactivity in Suzuki-Miyaura coupling. The electron-withdrawing trifluoromethoxy moiety promotes efficient cross-coupling under standard conditions, enabling rapid access to complex arylated scaffolds with improved functional group tolerance.
3-Chloro-2-(trifluoromethoxy)phenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The trifluoromethoxy group enhances metabolic stability and modulates lipophilicity, while the chloro substituent provides orthogonal reactivity for downstream functionalization. Bench-stable and readily purified by recrystallization, it facilitates the construction of complex aryl scaffolds relevant to medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: