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Structure of 916587-44-5
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Tert-butyl methyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate features a boronate ester group flanked by a sterically hindered tert-butyl carbamate and methyl substituent. This bench-stable reagent integrates readily into Suzuki-Miyaura coupling reactions under standard conditions, enabling efficient construction of biaryl architectures with minimal protodeboronation.
Tert-butyl methyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. The tert-butyl carbamate (Boc) group provides excellent protection for primary amines, enabling orthogonal functionalization in complex molecule synthesis. Its tetramethylborolane moiety ensures high reactivity under standard coupling conditions, with broad functional group tolerance and ease of purification. This reagent facilitates efficient construction of biaryl scaffolds and is well-suited for iterative synthetic strategies in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H317-H413
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Precautionary Statements : P261-P272-P273-P280-P302+P352-P363-P501
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Lot numbers can be found on the outside label of a product: