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CS-W001157 4
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NH2-PEG2-CH2-Boc

  • CAS No. 1948273-09-3

  • Cat. No. CS-B1495
  • Molecule weight233.30
  • Purity≥97%
  • MDL No.MFCD30741911

*For research and further manufacturing use only, not for direct human use.

NH2-PEG2-CH2-Boc|CS-B1495

Structure of 1948273-09-3

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General Information

  • CAS No. 1948273-09-3
  • Cat. No. CS-B1495
  • Purity ≥97%
  • MDL No. MFCD30741911
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₃NO₄
  • Molecular Weight 233.30
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)COCCCOCCN

Description

NH2-PEG2-CH2-Boc features a short ethylene glycol spacer flanked by a primary amine and a tert-butoxycarbonyl group, enabling selective conjugation and protection in peptide synthesis. This bifunctional scaffold supports efficient coupling reactions under mild conditions, with the Boc moiety providing robust protection that cleaves cleanly during acidic deprotection steps.

Application

NH2-PEG2-CH2-Boc serves as a versatile bifunctional building block for peptide and conjugate synthesis, combining a stable, hydrolytically resistant Boc-protected amine with a PEG2 spacer for enhanced solubility. The terminal primary amine enables facile coupling reactions, while the PEG2 linker improves bioavailability and reduces aggregation in biological applications. Functions reliably in standard solution-phase and solid-phase workflows, offering excellent handling stability and straightforward purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   70.78
  • LogP   0.7101
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   8

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