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Structure of 195044-14-5
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2-Bromo-6-(tert-butyl)pyridine features a sterically hindered tert-butyl group flanking a brominated pyridine core, enhancing stability and directing regioselective coupling in cross-coupling reactions. This bench-stable building block integrates efficiently into complex heterocyclic architectures under standard conditions.
2-Bromo-6-(tert-butyl)pyridine serves as a versatile building block in cross-coupling chemistry, enabling palladium-catalyzed transformations such as Suzuki-Miyaura and Negishi reactions. The tert-butyl group provides steric protection and enhances bench stability, while the ortho-bromo substituent offers high reactivity in C–C bond formation. Its functional group tolerance and ease of purification make it well-suited for constructing complex heterocyclic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: