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CS-W001157 4
Total: USD 88.00

3-Methyl-4-(trifluoromethyl)piperidin-4-ol hydrochloride

  • CAS No. 1951439-16-9

  • Cat. No. CS-0199354
  • Molecule weight219.63
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Methyl-4-(trifluoromethyl)piperidin-4-ol hydrochloride|CS-0199354

Structure of 1951439-16-9

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General Information

  • CAS No. 1951439-16-9
  • Cat. No. CS-0199354
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃ClF₃NO
  • Molecular Weight 219.63
  • Synonym(s) 3-Methyl-4-(Trifluoromethyl)Piperidin-4-Ol Hydrochloride(WX601435)
  • SMILES CC1CNCCC1(O)C(F)(F)F.Cl

Description

3-Methyl-4-(trifluoromethyl)piperidin-4-ol hydrochloride features a sterically hindered piperidine core bearing a trifluoromethyl group and a hydroxyl function, delivering enhanced metabolic stability and improved solubility under physiological conditions. This compound serves as a key scaffold in medicinal chemistry for targeting CNS disorders and kinase pathways.

Application

3-Methyl-4-(trifluoromethyl)piperidin-4-ol hydrochloride serves as a valuable building block in medicinal chemistry, enabling efficient access to bioactive piperidine scaffolds. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the hydrochloride salt ensures improved solubility and handling. The molecule functions as a versatile intermediate in the synthesis of kinase inhibitors and CNS-targeted compounds, offering excellent functional group tolerance and compatibility with standard coupling reactions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   1.331
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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