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CS-W001157 4
Total: USD 88.00

3,3'-Diindolylmethane

  • CAS No. 1968-05-4

  • Cat. No. CS-1652
  • Molecule weightNone
  • Purity≥98%
  • MDL No.MFCD00195766

*For research and further manufacturing use only, not for direct human use.

3,3'-Diindolylmethane|CS-1652

Structure of 1968-05-4

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General Information

  • CAS No. 1968-05-4
  • Cat. No. CS-1652
  • Purity ≥98%
  • MDL No. MFCD00195766
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₁₄N₂
  • Molecular Weight None
  • Synonym(s) DIM; Arundine; HB 236
  • SMILES C1(CC2=CNC3=C2C=CC=C3)=CNC4=C1C=CC=C4

Description

.

Application

3,3′-Diindolylmethane (CAS 1968-05-4) inhibits Th17 cell differentiation by disrupting IRF-7-driven plasmacytoid dendritic cell activation in psoriasis models. It targets autoimmune inflammation at the cellular level. Researchers leverage this to explore novel immunomodulatory therapies. A diindolylmethane-enriched diet protects against doxorubicin-induced heart damage in mice. Nanoformulated variants suppress breast cancer progression by altering apoptosis and angiogenesis. Synthetic glycoconjugates show promise as low-toxicity antileishmanial agents.

Synthesis

  • Route1
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      858232-12-9
    • ~%
    • In-stock
      3,3'-Diindolylmethane|CS-1652
      1968-05-4

    References

    • Chemische Berichte, , vol. 88, p. 1295,1305
  • Route2
    • null|null
      50-00-0
    • ~%
    • In-stock
      3,3'-Diindolylmethane|CS-1652
      1968-05-4

    References

    • Chemische Berichte, , vol. 87, p. 692,696
  • Route3
    • null|null
      408331-17-9
    • ~%
    • In-stock
      3,3'-Diindolylmethane|CS-1652
      1968-05-4

    References

    • Chemische Berichte, , vol. 88, p. 1295,1305

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335-H413
Precautionary Statements : P261-P264-P271-P273-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   31.58
  • LogP   4.24
  • H_Acceptors   0
  • H_Donors   2
  • Rotatable_Bonds   2

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