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Structure of 174648-98-7
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6-Nitro-1,2,3,4-tetrahydro-isoquinoline hydrochloride features a bench-stable, electron-deficient heterocyclic core with a para-nitro group enhancing reactivity in C–H functionalization. This salt form improves solubility and handling in synthetic workflows, enabling efficient incorporation into pharmaceutical intermediates and complex alkaloid scaffolds under standard conditions.
6-Nitro-1,2,3,4-tetrahydro-isoquinoline hydrochloride serves as a versatile intermediate in the synthesis of isoquinoline-based scaffolds. Its nitro group enables subsequent reduction to amine functionalities, while the protonated heterocyclic core offers enhanced solubility and stability in aqueous/organic media. This compound facilitates efficient functionalization in medicinal chemistry campaigns, particularly for building complex alkaloid-like architectures with predictable reactivity profiles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: