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Structure of 19689-97-5
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tert-Butyl hydroxy(methyl)carbamate serves as a stable, moisture-tolerant protecting group for primary amines in synthetic workflows. This bench-stable derivative enables efficient N-alkylation and subsequent deprotection under mild acidic conditions, facilitating streamlined peptide and heterocycle synthesis.
tert-Butyl hydroxy(methyl)carbamate serves as a stable, bench-friendly protecting group for primary amines, enabling efficient N–H functionalization in peptide synthesis and medicinal chemistry workflows. Its orthogonal stability to common reaction conditions facilitates selective deprotection under mild acidic conditions, while the resulting hydroxymethylamine intermediate supports downstream transformations including cyclizations and coupling reactions. The carbamate’s robustness simplifies purification and enhances compatibility with diverse synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: