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CS-W001157 4
Total: USD 88.00

Z-Thr-OH

  • CAS No. 19728-63-3

  • Cat. No. CS-W012607
  • Purity≥98%
  • MDL No.MFCD00065948

*For research and further manufacturing use only, not for direct human use.

Z-Thr-OH|CS-W012607

Structure of 19728-63-3

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General Information

  • CAS No. 19728-63-3
  • Cat. No. CS-W012607
  • Purity ≥98%
  • MDL No. MFCD00065948
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₅NO₅
  • Molecular Weight 253.25
  • Synonym(s) None
  • SMILES O[C@@H]([C@@H](C(O)=O)NC(OCC1=CC=CC=C1)=O)C

Description

Z-Thr-OH is a protected threonine derivative featuring a benzyloxycarbonyl (Z) group at the N-terminus and a free hydroxyl function at the side chain. This configuration enables direct incorporation into peptide synthesis workflows without additional activation, offering enhanced solubility and stability under standard conditions.

Application

Z-Thr-OH serves as a key chiral building block in peptide synthesis, offering robust stability and straightforward handling. The Z (benzyloxycarbonyl) group provides effective protection of the amine, enabling selective coupling reactions without racemization. Its tertiary hydroxyl functionality supports orthogonal derivatization, facilitating access to complex peptide architectures and heterocyclic scaffolds commonly found in medicinal chemistry campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   95.86
  • LogP   0.7468
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   5

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