Z-Thr-OH

Name: Z-Thr-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 19728-63-3
Cat. No. CS-W012607
Purity≥98%
MDL No.MFCD00065948

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 19728-63-3

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Description

Z-Thr-OH is a protected threonine derivative featuring a benzyloxycarbonyl (Z) group at the N-terminus and a free hydroxyl function at the side chain. This configuration enables direct incorporation into peptide synthesis workflows without additional activation, offering enhanced solubility and stability under standard conditions.

Application

Z-Thr-OH serves as a key chiral building block in peptide synthesis, offering robust stability and straightforward handling. The Z (benzyloxycarbonyl) group provides effective protection of the amine, enabling selective coupling reactions without racemization. Its tertiary hydroxyl functionality supports orthogonal derivatization, facilitating access to complex peptide architectures and heterocyclic scaffolds commonly found in medicinal chemistry campaigns.

General Information

CAS No. 19728-63-3
Cat. No. CS-W012607
Purity ≥98%
MDL No. MFCD00065948
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₁₅NO₅
Molecular Weight 253.25
Synonym(s) None
SMILES O[C@@H]([C@@H](C(O)=O)NC(OCC1=CC=CC=C1)=O)C

Computational Chemistry Data

TPSA 95.86
LogP 0.7468
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 5

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Threonine and derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Z-Thr-OH

CAS No. 19728-63-3

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