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Structure of 1978-39-8
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5-Fluoro-2-methoxyaniline features a fluorinated aromatic ring paired with a methoxy group, delivering enhanced electron density and metabolic stability. This combination enables selective coupling in pharmaceutical intermediates, particularly in kinase inhibitor scaffolds and bioactive heterocycles. The molecule exhibits robust bench stability and compatibility with standard amine functionalization protocols.
5-Fluoro-2-methoxyaniline serves as a valuable building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds via standard coupling reactions. Its ortho-methoxy and meta-fluoro substituents provide complementary reactivity for palladium-catalyzed cross-couplings and electrophilic substitutions, while offering enhanced stability and ease of purification compared to non-substituted analogs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: