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CS-W001157 4
Total: USD 88.00

4-(3-Bromophenyl)morpholine

  • CAS No. 197846-82-5

  • Cat. No. CS-0028751
  • Purity≥96%
  • MDL No.MFCD04112585

*For research and further manufacturing use only, not for direct human use.

4-(3-Bromophenyl)morpholine|CS-0028751

Structure of 197846-82-5

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General Information

  • CAS No. 197846-82-5
  • Cat. No. CS-0028751
  • Purity ≥96%
  • MDL No. MFCD04112585
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂BrNO
  • Molecular Weight 242.11
  • Synonym(s) N-(3-BroMophenyl)Morpholine
  • SMILES BrC1=CC(N2CCOCC2)=CC=C1

Description

4-(3-Bromophenyl)morpholine is a bench-stable, electron-rich heterocyclic compound featuring a brominated phenyl group attached to a morpholine ring. This structure enables efficient coupling in palladium-catalyzed cross-coupling reactions and serves as a key intermediate in the synthesis of bioactive molecules within medicinal chemistry and materials science applications.

Application

4-(3-Bromophenyl)morpholine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable aryl bromide functionality. The morpholine ring provides a polar, basic nitrogen that enhances solubility and offers a handle for further derivatization. Its bench-stable nature and compatibility with standard coupling conditions facilitate efficient synthesis of complex heterocyclic scaffolds and drug candidates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.47
  • LogP   2.2857
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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