Fmoc-Phe(3,4-DiF)-OH

Name: Fmoc-Phe(3,4-DiF)-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 198560-43-9
Cat. No. CS-W011642
Purity≥98%
MDL No.MFCD00672550

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 198560-43-9

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Fmoc-Phe(3,4-DiF)-OH features a fluorinated phenylalanine residue with dual fluorines at the meta and para positions, enhancing metabolic stability and membrane permeability. This derivative integrates readily into peptide chains during solid-phase synthesis, offering improved bioavailability and resistance to enzymatic degradation in biological assays.

Application

Fmoc-Phe(3,4-DiF)-OH serves as a valuable building block in peptide synthesis, offering enhanced metabolic stability and modulated lipophilicity through its 3,4-difluorophenyl side chain. The fluorinated aromatic ring improves resistance to oxidative metabolism while maintaining favorable solubility and compatibility with standard coupling protocols. This derivative facilitates the incorporation of electron-deficient phenylalanine analogs into bioactive peptides, enabling precise tuning of conformational and pharmacokinetic properties in medicinal chemistry campaigns.

General Information

CAS No. 198560-43-9
Cat. No. CS-W011642
Purity ≥98%
MDL No. MFCD00672550
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₄H₁₉F₂NO₄
Molecular Weight 423.41
Synonym(s) None
SMILES O=C(O)[C@H](CC1=CC=C(F)C(F)=C1)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Computational Chemistry Data

TPSA 75.63
LogP 4.4992
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 6

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Bioactive Molecules Peptides

Building Blocks Functional Group Fmoc

Life Science Amino Acids and their Derivatives Phenylalanine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Key Words

Fmoc-Phe(3,4-DiF)-OH sigmaFmoc-Phe(3,4-DiF)-OH manufacturerFmoc-Phe(3,4-DiF)-OH priceFmoc-Phe(3,4-DiF)-OH structureFmoc-Phe(3,4-DiF)-OH SDSbuy Fmoc-Phe(3,4-DiF)-OHFmoc-Phe(3,4-DiF)-OH supplierFmoc-Phe(3,4-DiF)-OH usesFmoc-Phe(3,4-DiF)-OH molecular weightprice of Fmoc-Phe(3,4-DiF)-OHFmoc-Phe(3,4-DiF)-OH chemical name formula of Fmoc-Phe(3,4-DiF)-OH

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Fmoc-Phe(3,4-DiF)-OH

CAS No. 198560-43-9

Recommended Products