H-Phe(3-F)-OH

Name: H-Phe(3-F)-OH
Brand: ChemScene
Availability: InStock
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CAS No. 19883-77-3
Cat. No. CS-0011429
Purity≥97%
MDL No.MFCD00066450

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 19883-77-3

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Description

H-Phe(3-F)-OH is a fluorinated phenylalanine derivative featuring a meta-fluoro substitution on the aromatic ring. This electron-withdrawing group enhances metabolic stability and modulates binding affinity in peptide-based applications. The hydroxyl terminus enables straightforward conjugation or further functionalization, making it valuable for bioconjugation and peptidomimetic design.

Application

H-Phe(3-F)-OH serves as a valuable building block for the synthesis of bioactive peptides and pharmaceutical intermediates. The meta-fluorophenylalanine residue enhances metabolic stability and modulates electronic properties, enabling improved receptor binding affinity in peptide-based drug candidates. Its bench-stable, crystalline nature facilitates straightforward handling and purification, while maintaining compatibility with standard solid-phase peptide synthesis protocols.

General Information

CAS No. 19883-77-3
Cat. No. CS-0011429
Purity ≥97%
MDL No. MFCD00066450
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₀FNO₂
Molecular Weight 183.18
Synonym(s) 3-Fluoro-L-phenylalanine; L-3-Fluorophenylalanine; m-Fluoro-L-phenylalanine; H-m-Fluoro-Phe-OH; H-Phe(3-F)-OH
SMILES FC1=CC(C[C@H](N)C(O)=O)=CC=C1

Computational Chemistry Data

TPSA 63.32
LogP 0.7801
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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H-Phe(3-F)-OH

CAS No. 19883-77-3

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