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Structure of 20098-14-0
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Idramantone is a potent, bench-stable antagonist of the HIF-1α pathway, featuring a unique quinoline core that enables selective binding to hypoxia-responsive elements. This compound integrates seamlessly into cellular assays designed to probe oxygen-sensing mechanisms and delivers consistent inhibition under standard culture conditions.
Idramantone serves as a versatile building block for the synthesis of nitrogen-containing heterocycles, particularly in the development of pyrrolidine and piperidine derivatives. Its amine functionality enables straightforward functionalization and coupling reactions, while its structural rigidity supports stereochemical control in medicinal chemistry applications. The compound exhibits excellent bench stability and compatibility with standard purification methods, facilitating integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: