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Structure of 201274-81-9
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H-D-Thr(tBu)-OH is a protected, non-natural amino acid derivative featuring a tert-butyl group at the β-position, offering enhanced stability and steric shielding. This configuration enables selective incorporation into peptide sequences under standard coupling conditions, facilitating the synthesis of conformationally restricted analogs with improved metabolic resilience.
H-D-Thr(tBu)-OH serves as a stable, bench-ready building block for the synthesis of peptidomimetics and bioactive oligomers. The tert-butyl-protected hydroxyl group enables orthogonal functionalization in complex sequences, while the D-threonine backbone provides stereochemical control in constrained peptide architectures. This derivative facilitates efficient coupling reactions and is compatible with standard solid-phase and solution-phase protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: