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Structure of 1068976-51-1
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2-Bromo-6-fluoropyridin-3-amine features a pyridine core bearing bromo and fluoro substituents at the 2- and 6-positions, respectively, with an amino group at the 3-position. This electron-deficient heterocycle enables direct coupling in cross-coupling reactions, serving as a key building block for bioactive molecules and pharmaceutical intermediates. The molecule exhibits enhanced stability under standard handling conditions.
2-Bromo-6-fluoropyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The bromine site facilitates efficient Suzuki, Stille, and Negishi couplings, while the fluorine enhances metabolic stability and modulates electronic properties. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302+H312-H315-H319-H331-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: