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CS-W001157 4
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1'-(tert-Butoxycarbonyl)-[1,4'-bipiperidine]-4-carboxylic acid

  • CAS No. 201810-59-5

  • Cat. No. CS-0047050
  • Molecule weight312.41
  • Purity≥95%
  • MDL No.MFCD06408960

*For research and further manufacturing use only, not for direct human use.

1'-(tert-Butoxycarbonyl)-[1,4'-bipiperidine]-4-carboxylic acid|CS-0047050

Structure of 201810-59-5

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General Information

  • CAS No. 201810-59-5
  • Cat. No. CS-0047050
  • Purity ≥95%
  • MDL No. MFCD06408960
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₈N₂O₄
  • Molecular Weight 312.41
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N1CCC(N2CCC(C(=O)O)CC2)CC1

Description

This protected bipiperidine derivative features a tert-butoxycarbonyl group that enables stable incorporation into peptide and small-molecule syntheses. The carboxylic acid functionality provides a reactive handle for amide coupling, while the rigid piperidine scaffold offers defined conformational control in bioactive compound design.

Application

1'-(tert-Butoxycarbonyl)-[1,4'-bipiperidine]-4-carboxylic acid serves as a versatile building block for the synthesis of complex nitrogen-containing scaffolds. The Boc-protected piperidine moiety enables stable storage and orthogonal deprotection, while the carboxylic acid functionality facilitates amide coupling and conjugation reactions. This compound functions effectively in solid-phase synthesis and solution-phase diversification, offering excellent functional group tolerance and ease of purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   70.08
  • LogP   2.1825
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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