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Structure of 202745-73-1
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1-Methyl-1H-indole-6-carboxylic acid features a sterically accessible carboxylic acid group positioned at the 6-position of a methylated indole core. This electron-rich heterocycle integrates readily into bioactive molecule scaffolds, offering enhanced solubility and metabolic stability in medicinal chemistry applications.
1-Methyl-1H-indole-6-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to indole-based scaffolds through standard amide coupling and electrophilic functionalization. The methyl group at the nitrogen enhances solubility and metabolic stability, while the carboxylic acid facilitates conjugation with amines and nucleophiles under common coupling conditions. Its bench-stable nature and compatibility with diverse reaction environments make it well-suited for high-throughput synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: