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CS-W001157 4
Total: USD 88.00

N-Benzylpiperazine-1-carboxamide

  • CAS No. 202819-47-4

  • Cat. No. CS-0293567
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N-Benzylpiperazine-1-carboxamide|CS-0293567

Structure of 202819-47-4

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General Information

  • CAS No. 202819-47-4
  • Cat. No. CS-0293567
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₇N₃O
  • Molecular Weight 219.28
  • Synonym(s) None
  • SMILES O=C(N1CCNCC1)NCC2=CC=CC=C2

Description

N-Benzylpiperazine-1-carboxamide features a piperazine core functionalized with a benzyl group and a carboxamide moiety, enabling robust hydrogen bonding and enhanced solubility. This structural combination supports integration into bioactive scaffolds for medicinal chemistry applications, offering favorable handling characteristics under standard conditions.

Application

N-Benzylpiperazine-1-carboxamide serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard amide coupling and reductive amination protocols. Its piperazine core provides enhanced solubility and metabolic stability, while the benzyl group offers favorable π-stacking interactions in target binding. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for high-throughput synthesis and lead optimization campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   44.37
  • LogP   0.8014
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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