(S)-3-Aminotetrahydrofuran hydrochloride

Name: (S)-3-Aminotetrahydrofuran hydrochloride
Brand: ChemScene
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CAS No. 204512-95-8
Cat. No. CS-W019697
Purity≥97%
MDL No.MFCD08445642

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(S)-3-Aminotetrahydrofuran hydrochloride|CS-W019697

Structure of 204512-95-8

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Description

(S)-3-Aminotetrahydrofuran hydrochloride is a chiral heterocyclic amine offering high enantiomeric purity for asymmetric synthesis. This bench-stable, moisture-tolerant building block integrates readily into medicinal chemistry campaigns, where its constrained tetrahydrofuran scaffold supports stereocontrolled functionalization and enhances metabolic stability in bioactive molecules.

Application

(S)-3-Aminotetrahydrofuran hydrochloride serves as a valuable chiral building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its well-defined stereochemistry and amine functionality facilitate direct incorporation into peptide mimetics and nitrogen-containing scaffolds. The hydrochloride salt enhances stability and solubility, supporting straightforward handling and purification in standard synthetic workflows.

General Information

CAS No. 204512-95-8
Cat. No. CS-W019697
Purity ≥97%
MDL No. MFCD08445642
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₁₀ClNO
Molecular Weight 123.58
Synonym(s) (S)-Tetrahydrofuran-3-amine hydrochloride; (S)-Tetrahydrofuran-3-ylamine hydrochloride; (3S)-tetrahydrofuran-3-amine hydrochloride
SMILES N[C@@H]1COCC1.[H]Cl

Computational Chemistry Data

TPSA 35.25
LogP 0.1558
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Tetrahydrofuran compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-3-Aminotetrahydrofuran hydrochloride

CAS No. 204512-95-8

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