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CS-W001157 4
Total: USD 88.00

4,4'-Oxybis(bromobenzene)

  • CAS No. 2050-47-7

  • Cat. No. CS-0139872
  • Purity≥97%
  • MDL No.MFCD00000095

*For research and further manufacturing use only, not for direct human use.

4,4'-Oxybis(bromobenzene)|CS-0139872

Structure of 2050-47-7

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General Information

  • CAS No. 2050-47-7
  • Cat. No. CS-0139872
  • Purity ≥97%
  • MDL No. MFCD00000095
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₈Br₂O
  • Molecular Weight 328.00
  • Synonym(s) ether, bis(4-bromophenyl)
  • SMILES BrC1=CC=C(OC2=CC=C(Br)C=C2)C=C1

Description

Bis-(4-bromophenyl)-ether has been used in the preparation of 4-[4-(diethoxyphosphoryl)phenoxy]phenyl-phosphonic acid diethyl ester.

Application

4,4'-Oxybis(bromobenzene) serves as a versatile bifunctional building block in cross-coupling and polymer synthesis, enabling the construction of conjugated backbones and functionalized aromatic architectures. Its stability under standard reaction conditions and orthogonal reactivity facilitate efficient Pd-catalyzed coupling processes, including Suzuki-Miyaura and Stille reactions. The molecule’s dual bromine substituents and ether linkage provide predictable regiochemistry and excellent purification characteristics, making it well-suited for scalable synthesis of advanced materials and pharmaceutical intermediates.

Synthesis

  • Route1
    • null|null
      101-84-8
    • ~97%
    • In-stock
      4,4'-Oxybis(bromobenzene)|CS-0139872
      2050-47-7

    References

    • Bromine Compounds Ltd. Patent: EP429975 A1, 1991 ;
  • Route2
    • null|null
      101-84-8
    • null|null
      107-06-2
    • ~98%
    • In-stock
      4,4'-Oxybis(bromobenzene)|CS-0139872
      2050-47-7

    References

    • Bromine Compounds Ltd. Patent: EP429975 A1, 1991 ;
  • Route3

    References

    • Tlili, Anis; Monnier, Florian; Taillefer, Marc Chemistry - A European Journal, 2010 , vol. 16, # 41 p. 12299 - 12302

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   5.0039
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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