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CS-W001157 4
Total: USD 88.00

5-Chlorobenzothiophene

  • CAS No. 20532-33-6

  • Cat. No. CS-W002268
  • Purity≥98%
  • MDL No.MFCD00055623
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Chlorobenzothiophene|CS-W002268

Structure of 20532-33-6

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Description

5-Chlorobenzothiophene is a heterocyclic aromatic compound featuring a chlorine substituent at the 5-position of the benzothiophene core. This electron-deficient scaffold integrates readily into medicinal chemistry libraries, offering enhanced metabolic stability and favorable lipophilic character for target engagement in kinase inhibition and GPCR modulation studies.

Application

5-Chlorobenzothiophene serves as a versatile building block in medicinal chemistry and materials science, enabling direct functionalization at the 2- and 3-positions via palladium-catalyzed cross-coupling reactions. Its robust heterocyclic core exhibits excellent bench stability, moderate solubility in common organic solvents, and tolerance to a range of reaction conditions, facilitating efficient incorporation into complex molecular architectures.

General Information

  • CAS No. 20532-33-6
  • Cat. No. CS-W002268
  • Purity ≥98%
  • MDL No. MFCD00055623
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅ClS
  • Molecular Weight 168.64
  • Synonym(s) Benzo[b]thiophene, 5-chloro-
  • SMILES Clc1ccc2c(c1)ccs2

Computational Chemistry Data

  • TPSA   0
  • LogP   3.5547
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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