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Structure of 205444-22-0
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2-Chloro-4-iodo-6-(trifluoromethyl)pyridine features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the orthogonal halogen substituents enable sequential cross-coupling reactions. This pyridine scaffold serves as a key building block for bioactive molecules in medicinal chemistry and agrochemical development.
2-Chloro-4-iodo-6-(trifluoromethyl)pyridine serves as a versatile heterocyclic building block for Suzuki-Miyaura and Buchwald-Hartwig coupling reactions. The ortho-chloro and meta-iodo substituents enable sequential functionalization, while the trifluoromethyl group enhances metabolic stability and lipophilicity. Bench-stable and compatible with diverse reaction conditions, it facilitates efficient access to complex pyridyl scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: