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Structure of 590371-73-6
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4-Iodo-2-(trifluoromethyl)pyridine features a trifluoromethyl group flanking a reactive iodine at the pyridine ring's 4-position, enabling efficient cross-coupling transformations. This electron-deficient heterocycle integrates readily into pharmaceutical scaffolds and functional materials under standard conditions.
4-Iodo-2-(trifluoromethyl)pyridine serves as a versatile building block in cross-coupling chemistry, enabling efficient Suzuki, Stille, and Negishi reactions due to its stable iodide functionality and electron-deficient pyridine core. The trifluoromethyl group enhances metabolic stability and lipophilicity, making it valuable for medicinal chemistry applications. Its bench-stable, crystalline form facilitates handling and purification, supporting scalable synthesis of heterocyclic scaffolds and functionalized API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: