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Structure of 205448-31-3
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4-Chloro-6-methoxyquinolin-7-ol features a quinoline scaffold with strategic electron-withdrawing and donor substituents, enabling its use in cross-coupling reactions and as a building block for bioactive heterocycles. The chloro group at C4 facilitates palladium-catalyzed transformations, while the methoxy and hydroxyl functionalities provide sites for further functionalization. This compound exhibits good stability under standard handling conditions.
4-Chloro-6-methoxyquinolin-7-ol serves as a versatile building block in medicinal chemistry, enabling efficient construction of quinoline-based scaffolds. Its orthogonal functional groups—chloro at C4, methoxy at C6, and phenolic hydroxyl at C7—facilitate diverse transformations including Suzuki-Miyaura coupling, nucleophilic substitution, and directed metalation. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: