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Aminooxy-PEG3-C2-NH-Boc

  • CAS No. 2062663-65-2

  • Cat. No. CS-0114353
  • Purity≥97%
  • MDL No.MFCD30536148

*For research and further manufacturing use only, not for direct human use.

Aminooxy-PEG3-C2-NH-Boc|CS-0114353

Structure of 2062663-65-2

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General Information

  • CAS No. 2062663-65-2
  • Cat. No. CS-0114353
  • Purity ≥97%
  • MDL No. MFCD30536148
  • Storage 4°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₈N₂O₆
  • Molecular Weight 308.37
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCOCCOCCOCCON

Description

Aminooxy-PEG3-C2-NH-Boc features a hydrophilic PEG3 spacer flanked by aminooxy and Boc-protected amine functionalities, enabling site-specific conjugation in bioconjugation workflows. The electron-rich aminooxy group facilitates efficient oxime ligation, while the bench-stable Boc handle permits controlled deprotection under mild acidic conditions. This bifunctional architecture supports modular synthesis of glycoconjugates and targeted probes.

Application

Aminooxy-PEG3-C2-NH-Boc serves as a versatile bifunctional linker for conjugation and protection strategies in synthetic chemistry. The aminooxy group enables efficient oxime ligation with aldehydes or ketones, while the PEG3 spacer provides solubility and reduced aggregation. The C2 linker offers optimal spacing, and the Boc-protected amine allows for selective deprotection under mild acidic conditions. This compound facilitates site-specific bioconjugation and is well-suited for peptide modification, probe synthesis, and the construction of functionalized scaffolds in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   101.27
  • LogP   0.4512
  • H_Acceptors   7
  • H_Donors   2
  • Rotatable_Bonds   12

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