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Structure of 208110-81-0
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6-Fluoropyridine-2-carboxaldehyde features a fluorinated pyridine ring paired with an aldehyde group at the 2-position, enabling direct incorporation into diverse heterocyclic architectures. The electron-deficient aromatic system enhances reactivity in nucleophilic addition and condensation processes. This bench-stable reagent facilitates efficient synthesis of bioactive compounds and functional materials under standard conditions.
6-Fluoropyridine-2-carboxaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient construction of bioactive heterocycles through nucleophilic addition and condensation reactions. Its ortho-aldehyde functionality exhibits high reactivity with amines and hydrazines, facilitating rapid access to imines, hydrazones, and pyridine-based scaffolds. The fluorine substituent enhances metabolic stability and modulates electronic properties, offering favorable lipophilicity and target affinity. Bench-stable and readily purified by distillation or flash chromatography, it functions reliably in multistep synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: