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Structure of 402-69-7
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2-Fluoropyridine-6-carboxylic acid features a strategically positioned fluorine atom and carboxylic acid group on a pyridine ring, enabling robust integration into pharmaceutical scaffolds. This electron-deficient heterocycle offers enhanced metabolic stability and facilitates directed functionalization in medicinal chemistry. The acidic proton enables salt formation and conjugation, supporting purification and derivatization under standard conditions.
2-Fluoropyridine-6-carboxylic acid serves as a versatile building block for medicinal chemistry and agrochemical synthesis, enabling direct incorporation of fluorinated pyridine motifs into bioactive scaffolds. Its carboxylic acid functionality facilitates amide coupling, esterification, and metal-catalyzed cross-coupling reactions, while the ortho-fluoro group supports nucleophilic aromatic substitution and directed metalation. The compound exhibits good bench stability and is readily purified by recrystallization, making it suitable for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: