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CS-W001157 4
Total: USD 88.00

2,5-Diiodoterephthalic acid

  • CAS No. 20856-80-8

  • Cat. No. CS-0379208
  • Purity≥98%
  • MDL No.MFCD02311930
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,5-Diiodoterephthalic acid|CS-0379208

Structure of 20856-80-8

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Description

2,5-Diiodoterephthalic acid features two iodine substituents at the para positions of a terephthalic acid core, enabling efficient coupling in palladium-catalyzed cross-coupling reactions. This electron-deficient aromatic diacid integrates readily into functionalized polymer backbones and metal-organic frameworks, offering robust structural integrity under thermal and oxidative conditions.

Application

2,5-Diiodoterephthalic acid serves as a versatile building block for constructing iodinated aromatic scaffolds in medicinal chemistry and materials science. Its orthogonal reactivity enables selective Suzuki-Miyaura coupling under standard conditions, facilitating the assembly of complex biaryls and functionalized polyaromatic systems. The carboxylic acid groups provide additional handles for derivatization, while the diiodo substitution offers high stability and ease of purification—ideal for bench-scale synthesis and downstream integration into API candidates or advanced organic semiconductors.

General Information

  • CAS No. 20856-80-8
  • Cat. No. CS-0379208
  • Purity ≥98%
  • MDL No. MFCD02311930
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄I₂O₄
  • Molecular Weight 417.92
  • Synonym(s) 2,5-Diiodo-1,4-dibenzoic acid
  • SMILES O=C(O)C1=CC(I)=C(C=C1I)C(=O)O

Computational Chemistry Data

  • TPSA   74.6
  • LogP   2.2922
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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