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Structure of 1176754-31-6
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1-Methyl-1H-indazole-5-carboxylic acid features a fused bicyclic core with a methylated indazole ring and a carboxylic acid at the 5-position, enabling direct conjugation or derivatization. This structural motif delivers enhanced solubility and metabolic stability in bioactive molecule design.
1-Methyl-1H-indazole-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions under standard conditions. The indazole core provides structural rigidity and favorable pharmacophoric properties, while the methyl group enhances metabolic stability and modulates solubility. Bench-stable and readily purified by recrystallization, it functions reliably in peptide conjugation, macrocyclization, and scaffold diversification workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: