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Structure of 208641-98-9
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This boronic acid features a difluorinated aromatic core paired with a methoxy substituent, enhancing electron deficiency and stability. The ortho-fluorine atoms facilitate selective cross-coupling reactions, while the methoxy group improves solubility and modulates reactivity under standard conditions.
(3,5-Difluoro-4-methoxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds with enhanced metabolic stability. Its fluorinated aryl core provides favorable electronic properties and improved solubility, while the boronic acid functionality offers excellent bench stability and compatibility with diverse reaction conditions. The methoxy group enhances regioselectivity and facilitates downstream functionalization, making it a practical choice for medicinal chemistry and process-scale synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: