2-(4-Bromo-1H-pyrazol-1-yl)-2-methylpropanenitrile

Name: 2-(4-Bromo-1H-pyrazol-1-yl)-2-methylpropanenitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 2088840-42-8
Cat. No. CS-0179466
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-(4-Bromo-1H-pyrazol-1-yl)-2-methylpropanenitrile|CS-0179466

Structure of 2088840-42-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

2-(4-Bromo-1H-pyrazol-1-yl)-2-methylpropanenitrile features a sterically hindered nitrile group flanked by a brominated pyrazole ring, enabling direct integration into cross-coupling reactions. The electron-deficient pyrazole moiety enhances reactivity in palladium-catalyzed transformations, while the tert-butyl-like structure confers bench stability and ease of handling under standard conditions.

Application

2-(4-Bromo-1H-pyrazol-1-yl)-2-methylpropanenitrile serves as a versatile building block for constructing pyrazole-based scaffolds in medicinal chemistry and materials science. The nitrile group enables downstream functionalization via hydrolysis or nucleophilic addition, while the bromo substituent supports palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. Its tert-butyl-like steric profile enhances bench stability and simplifies purification, making it well-suited for scalable synthesis and modular library development.

General Information

CAS No. 2088840-42-8
Cat. No. CS-0179466
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₈BrN₃
Molecular Weight 214.06
Synonym(s) None
SMILES N#CC(C)(C)N1N=CC(Br)=C1

Computational Chemistry Data

TPSA 41.61
LogP 1.90428
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Key Words

2088840-42-8 sigma2088840-42-8 manufacturer2088840-42-8 price2088840-42-8 structure2088840-42-8 SDSbuy 2088840-42-82088840-42-8 supplier2088840-42-8 uses2088840-42-8 molecular weightprice of 2088840-42-82088840-42-8 chemical name formula of 2088840-42-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-(4-Bromo-1H-pyrazol-1-yl)-2-methylpropanenitrile

CAS No. 2088840-42-8

Recommended Products