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Structure of 2089319-25-3
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(3,5-Dichloropyrazin-2-yl)methanamine hydrochloride delivers a highly reactive pyrazine scaffold bearing two chlorine substituents at electron-deficient positions. This bench-stable derivative integrates readily into medicinal chemistry campaigns requiring strong electron-withdrawing character and directional reactivity. The hydrochloride salt enhances solubility in polar solvents, streamlining purification and handling under standard conditions.
(3,5-Dichloropyrazin-2-yl)methanamine hydrochloride serves as a versatile building block for the synthesis of pyrazine-based pharmaceutical intermediates and agrochemicals. Its dual functional groups—primary amine and electron-deficient pyrazine ring—enable straightforward coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig aminations. The hydrochloride salt enhances bench stability and simplifies purification, while the dichloro substitution pattern supports selective functionalization in late-stage diversification strategies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: