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Structure of 20925-27-3
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4-Amino-2-chlorobenzonitrile features a strategically positioned amino group and chloro substituent on a nitrile-bearing benzene scaffold, enabling its use in coupling reactions and as a building block for pharmaceutical intermediates. This electron-rich aryl halide integrates readily into diverse synthetic pathways under standard conditions.
4-Amino-2-chlorobenzonitrile serves as a versatile building block in medicinal chemistry, enabling direct incorporation into heterocyclic scaffolds via cyclization or coupling reactions. Its ortho-chloro and nitrile groups provide complementary reactivity for palladium-catalyzed cross-couplings and nucleophilic substitution, while the amino functionality allows for derivatization through acylation or diazotization. Bench-stable and readily purified by recrystallization, it functions efficiently in multi-step syntheses requiring functional group tolerance and predictable regiochemistry.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302+H312-H315-H319-H331-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: