2-Methoxy-4-morpholinoaniline

Name: 2-Methoxy-4-morpholinoaniline
Brand: ChemScene
Availability: InStock
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CAS No. 209960-91-8
Cat. No. CS-0147956
Purity≥95%
MDL No.MFCD09972210

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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2-Methoxy-4-morpholinoaniline|CS-0147956

Structure of 209960-91-8

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Description

2-Methoxy-4-morpholinoaniline features a morpholino group that enhances solubility and electron-donating capacity, while the methoxy substituent stabilizes the aromatic system. This combination enables efficient coupling in amide bond formation and facilitates incorporation into complex molecular architectures under standard conditions.

Application

2-Methoxy-4-morpholinoaniline serves as a versatile building block in medicinal chemistry, enabling the synthesis of diverse heterocyclic scaffolds and bioactive compounds. Its ortho-methoxy and para-morpholino substituents provide complementary reactivity for coupling reactions and facilitate solubility and metabolic stability in target molecules. The compound exhibits good bench stability and is readily amenable to standard functional group transformations, making it a practical choice for lead optimization campaigns.

General Information

CAS No. 209960-91-8
Cat. No. CS-0147956
Purity ≥95%
MDL No. MFCD09972210
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₆N₂O₂
Molecular Weight 208.26
Synonym(s) 2-Methoxy-4-morpholinobenzenamine
SMILES NC1=CC=C(N2CCOCC2)C=C1OC

Computational Chemistry Data

TPSA 47.72
LogP 1.114
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Morpholine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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2-Methoxy-4-morpholinoaniline

CAS No. 209960-91-8

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