(R)-7-Chloro-2,3-dihydrobenzofuran-3-amine hydrochloride

Name: (R)-7-Chloro-2,3-dihydrobenzofuran-3-amine hydrochloride
Brand: ChemScene
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CAS No. 2102410-13-7
Cat. No. CS-0196997
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(R)-7-Chloro-2,3-dihydrobenzofuran-3-amine hydrochloride|CS-0196997

Structure of 2102410-13-7

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General Information

CAS No. 2102410-13-7
Cat. No. CS-0196997
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₉Cl₂NO
Molecular Weight 206.07
Synonym(s) (3R)-7-CHLORO-2,3-DIHYDRO-1-BENZOFURAN-3-AMINE HYDROCHLORIDE
SMILES O1C[C@@H](C=2C1=C(C=CC2)Cl)N.Cl

Description

(R)-7-Chloro-2,3-dihydrobenzofuran-3-amine hydrochloride is a chiral building block featuring a chlorine-substituted dihydrobenzofuran core with a primary amine functionality. This bench-stable salt form enhances solubility and handling in synthetic workflows, enabling efficient incorporation into bioactive molecule scaffolds. The stereochemistry at the 3-position ensures high enantioselectivity in downstream transformations.

Application

(R)-7-Chloro-2,3-dihydrobenzofuran-3-amine hydrochloride serves as a valuable chiral building block for the synthesis of bioactive heterocycles. Its well-defined stereochemistry and stable hydrochloride salt form enable reliable handling and purification. The molecule functions as a key intermediate in constructing substituted benzofurans, facilitating coupling reactions and downstream derivatization in medicinal chemistry campaigns.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

TPSA 35.25
LogP 2.154
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic heterocycle compounds Benzofuran compounds

Key Words

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(R)-7-Chloro-2,3-dihydrobenzofuran-3-amine hydrochloride

CAS No. 2102410-13-7

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