2-Amino-4-(4-bromophenyl)thiazole

Name: 2-Amino-4-(4-bromophenyl)thiazole
Brand: ChemScene
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CAS No. 2103-94-8
Cat. No. CS-W010183
Purity≥98%
MDL No.MFCD00051953

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2-Amino-4-(4-bromophenyl)thiazole|CS-W010183

Structure of 2103-94-8

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Description

2-Amino-4-(4-bromophenyl)thiazole features a brominated phenyl group attached to a thiazole core, delivering enhanced electron-withdrawing character and improved solubility in polar organic solvents. This scaffold integrates readily into heterocyclic libraries for medicinal chemistry applications, offering a robust platform for developing kinase inhibitors and bioactive compounds under standard bench conditions.

Application

2-Amino-4-(4-bromophenyl)thiazole serves as a versatile building block in medicinal chemistry, enabling efficient access to thiazole-based heterocycles via Suzuki-Miyaura and Buchwald-Hartwig coupling reactions. The bromophenyl moiety facilitates palladium-catalyzed cross-couplings, while the amino group supports derivatization for targeted scaffold optimization. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step synthesis workflows.

General Information

CAS No. 2103-94-8
Cat. No. CS-W010183
Purity ≥98%
MDL No. MFCD00051953
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₇BrN₂S
Molecular Weight 255.13
Synonym(s) 4-(4-Bromophenyl)-2-thiazolamine
SMILES NC1=NC(=CS1)C1=CC=C(Br)C=C1

Computational Chemistry Data

TPSA 38.91
LogP 3.1548
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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2-Amino-4-(4-bromophenyl)thiazole

CAS No. 2103-94-8

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