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Structure of 2106-49-2
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1-Chloro-2-fluoro-3-nitrobenzene features a trifunctional aromatic core with orthogonal reactivity, enabling selective transformations in late-stage functionalization. The electron-deficient ring supports efficient nucleophilic substitution, while the fluorine atom facilitates palladium-catalyzed coupling. This bench-stable compound serves as a key intermediate in pharmaceutical and agrochemical synthesis.
1-Chloro-2-fluoro-3-nitrobenzene serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The nitro group facilitates subsequent reduction and functionalization, while the fluorine atom enhances metabolic stability in pharmaceutical intermediates. Its bench-stable nature and compatibility with diverse reaction conditions make it a practical choice for constructing complex heterocyclic scaffolds and API precursors.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H312-H315-H319-H331-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: