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Structure of 211244-81-4
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This pyrido[2,3-d]pyrimidinone scaffold features a methylthio group at the 2-position, enhancing lipophilicity and metabolic stability. The fused heterocyclic core provides rigidity and favorable electronic properties, enabling efficient integration into kinase inhibitor scaffolds and medicinal chemistry campaigns targeting ATP-binding sites.
2-(Methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to purine analogs and kinase inhibitor scaffolds. Its methylthio group offers moderate stability and facilitates subsequent functionalization via oxidation or displacement reactions. The core pyrido[2,3-d]pyrimidin-7(8H)-one framework exhibits favorable solubility and bench stability, supporting straightforward purification and integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: