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Structure of 886372-98-1
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5-Bromo-2-fluoro-3-nitropyridine features a trifunctional pyridine core with bromo, fluoro, and nitro groups positioned for orthogonal reactivity. This electron-deficient heterocycle enables direct coupling in cross-coupling and nucleophilic substitution reactions. The strategic placement of substituents supports efficient functionalization under mild conditions while maintaining stability during storage and handling.
5-Bromo-2-fluoro-3-nitropyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The nitro group facilitates electrophilic substitution and subsequent reduction to an amine, while the fluorine atom provides orthogonal reactivity for late-stage functionalization. Bench-stable and compatible with standard purification protocols, it functions effectively in the synthesis of heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: