(R)-Chroman-3-amine hydrochloride

Name: (R)-Chroman-3-amine hydrochloride
Brand: ChemScene
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CAS No. 211506-59-1
Cat. No. CS-0137501
Purity≥98%
MDL No.MFCD22689215

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-Chroman-3-amine hydrochloride|CS-0137501

Structure of 211506-59-1

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Description

(R)-Chroman-3-amine hydrochloride is a chiral amine scaffold featuring a rigid chroman core, offering enhanced stereochemical control in asymmetric synthesis. The hydrochloride salt form ensures improved solubility and stability under standard handling conditions, facilitating its use in medicinal chemistry and catalyst development.

Application

(R)-Chroman-3-amine hydrochloride serves as a versatile chiral building block for medicinal chemistry, enabling efficient access to bioactive heterocycles. Its stable hydrochloride salt form enhances bench handling and purification, while the amine functionality facilitates straightforward derivatization via amidation, alkylation, and reductive amination. This compound functions as a key scaffold in the synthesis of kinase inhibitors and CNS-targeted pharmaceuticals, offering predictable stereochemical control in multi-step sequences.

General Information

CAS No. 211506-59-1
Cat. No. CS-0137501
Purity ≥98%
MDL No. MFCD22689215
Storage Store at room temperature, keep dry and cool
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₂ClNO
Molecular Weight 185.65
Synonym(s) (R)-Chroman-3-ylamine hydrochloride
SMILES N[C@H]1COC2=CC=CC=C2C1.[H]Cl

Computational Chemistry Data

TPSA 35.25
LogP 1.3706
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Other aromatic heterocycles compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-Chroman-3-amine hydrochloride

CAS No. 211506-59-1

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