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Structure of 21203-68-9
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2-Methyl-5-nitropyridine features a nitro group at the pyridine ring's para position relative to a methyl substituent, creating a strongly electron-deficient heteroaromatic system. This configuration enables direct coupling in cross-coupling reactions and facilitates functionalization under mild conditions. The molecule exhibits enhanced solubility in organic solvents and stability under standard bench protocols, making it a robust scaffold for medicinal chemistry and materials synthesis.
2-Methyl-5-nitropyridine serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling efficient access to functionalized pyridine derivatives. Its nitro group facilitates nucleophilic substitution and reduction to an amine, while the methyl substituent provides a handle for further functionalization. The compound exhibits good bench stability and compatibility with standard reaction conditions, making it valuable for constructing complex scaffolds in API development and catalyst design.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: